Melanoma Research Today is a free monthly online journal that collates and summarizes the latest research about Melanoma, including details on identification, causes, prevention, treatment.

Volume 2 (2005), Issue 6 (June)

1. Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS.
   Br J Cancer, 92(11): 2032-8. [Abstract] [Full-text]
2. Outcome in 846 cutaneous melanoma patients from a single center after a negative sentinel node biopsy.
   Ann Surg Oncol, 12(6): 429-39. [Abstract] [Full-text]
3. Treatment of liver metastases from uveal melanoma.
   Ann Surg Oncol, 12(6): 422-8. [Abstract] [Full-text]
4. Phase I trial combining gemcitabine and treosulfan in advanced cutaneous and uveal melanoma patients.
   Br J Cancer, 92(11): 1997-2003. [Abstract] [Full-text]
5. Mitotic rate as a predictor of sentinel lymph node positivity in patients with thin melanomas.
   Ann Surg Oncol, 12(6): 449-58. [Abstract] [Full-text]
6. Sentinel lymph node tumor load: an independent predictor of additional lymph node involvement and survival in melanoma.
   Ann Surg Oncol, 12(6): 440-8. [Abstract] [Full-text]
7. Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study.
   J Cell Physiol, 204(2): 522-31. [Abstract] [Full-text]
8. Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells.
   J Clin Invest, 115(6): 1616-26. [Abstract] [Full-text]
9. Toward improved immunocompetence of adoptively transferred CD8+ T cells.
   J Clin Invest, 115(6): 1467-9. [Abstract] [Full-text]
10. Phase I study of the intratumoral administration of recombinant canarypox viruses expressing B7.1 and interleukin 12 in patients with metastatic melanoma.
    Clin Cancer Res, 11(11): 4168-75. [Abstract] [Full-text]
11. Inhibition of endogenous reverse transcriptase antagonizes human tumor growth.
    Oncogene, 24(24): 3923-31. [Abstract] [Full-text]
12. Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case-control study.
    Carcinogenesis, 26(6): 1085-90. [Abstract] [Full-text]
13. WST11, a novel water-soluble bacteriochlorophyll derivative; cellular uptake, pharmacokinetics, biodistribution and vascular-targeted photodynamic activity using melanoma tumors as a model.
    Photochem Photobiol, 81(2): 342-51. [Abstract] [Full-text]
14. Community perceptions of suspicious pigmented skin lesions: are they accurate when compared to general practitioners?
    Cancer Detect Prev, 29(3): 267-75. [Abstract] [Full-text]
15. Control of melanoma cell invasion by type IV collagen.
    Cancer Detect Prev, 29(3): 260-6. [Abstract] [Full-text]
16. Anti-tumoral effect of native and immobilized bovine serum amine oxidase in a mouse melanoma model.
    Biochem Pharmacol, 69(12): 1693-704. [Abstract] [Full-text]
17. Tumor, node, metastasis classification of malignant ciliary body and choroidal melanoma evaluation of the 6th edition and future directions.
    Ophthalmology, 112(6): 1135-44. [Abstract] [Full-text]
18. Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
    Cancer Chemother Pharmacol, 56(2): 126-37. [Abstract] [Full-text]
19. Metastatic malignant melanoma presenting as pancytopenia in a three-year-old boy.
    Pediatr Blood Cancer, 45(1): 60-3. [Abstract] [Full-text]
20. In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative.
    Cancer Chemother Pharmacol, 56(2): 115-25. [Abstract] [Full-text]
21. Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo.
    Proc Natl Acad Sci U S A, 102(23): 8293-8. [Abstract] [Full-text]
22. A phase II study of bortezomib in the treatment of metastatic malignant melanoma.
    Cancer, 103(12): 2584-9. [Abstract] [Full-text]
23. Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study.
    Cancer, 103(12): 2590-7. [Abstract] [Full-text]
24. Induction of tumor immunity and cytotoxic t lymphocyte responses using dendritic cells transduced by adenoviral vectors encoding HBsAg: comparison to protein immunization.
    J Cancer Res Clin Oncol, 131(7): 429-38. [Abstract] [Full-text]
25. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response.
    J Cancer Res Clin Oncol, 131(7): 468-78. [Abstract] [Full-text]
26. Nuclear sphingomyelin-synthase and protein kinase C delta in melanoma cells.
    Arch Biochem Biophys, 438(2): 156-61. [Abstract] [Full-text]
27. Human malignant melanoma: detection of BRAF- and c-kit-activating mutations by high-resolution amplicon melting analysis.
    Hum Pathol, 36(5): 486-93. [Abstract] [Full-text]
28. Expression of melanoma-associated antigens in melanoma cell cultures.
    Exp Dermatol, 14(7): 491-7. [Abstract] [Full-text]
29. Comparison of dermoscopic and histopathological findings in a mucous melanoma of the lip.
    Br J Dermatol, 152(6): 1324-6. [Abstract] [Full-text]
30. Outcomes and pathological review of a cohort of children with melanoma.
    Br J Dermatol, 152(6): 1321-3. [Abstract] [Full-text]
31. Management of melanoma metastasis to the breast: case series and review of the literature.
    Br J Dermatol, 152(6): 1206-10. [Abstract] [Full-text]
32. Echographic examination with new generation contrast agent of choroidal malignant melanomas.
    Acta Ophthalmol Scand, 83(3): 347-54. [Abstract] [Full-text]
33. Photobiology of ocular melanocytes and melanoma.
    Photochem Photobiol, 81(3): 506-9. [Abstract] [Full-text]
34. Histologic similarities between lentigo maligna and dysplastic nevus: importance of clinicopathologic distinction.
    J Cutan Pathol, 32(6): 405-12. [Abstract] [Full-text]
35. Transforming growth factor-beta and malignant melanoma: molecular mechanisms.
    J Cutan Pathol, 32(6): 389-95. [Abstract] [Full-text]
36. Sun protection initiatives in Cornwall.
    Clin Exp Dermatol, 30(4): 340-3. [Abstract] [Full-text]
37. Transfection of melanoma cells with antisense PAX3 oligonucleotides additively complements cisplatin-induced cytotoxicity.
    Mol Cancer Ther, 4(6): 996-1003. [Abstract] [Full-text]
38. Clusterin regulates drug-resistance in melanoma cells.
    J Invest Dermatol, 124(6): 1300-7. [Abstract] [Full-text]
39. The non-receptor-associated tyrosine kinase Syk is a regulator of metastatic behavior in human melanoma cells.
    J Invest Dermatol, 124(6): 1293-9. [Abstract] [Full-text]
40. Synthesis and identification of small molecules that potently induce apoptosis in melanoma cells through G1 cell cycle arrest.
    J Am Chem Soc, 127(24): 8686-96. [Abstract] [Full-text]
41. Search for germline alterations in CDKN2A/ARF and CDK4 of 42 Jewish melanoma families with or without neural system tumours.
    Br J Cancer, 92(12): 2278-85. [Abstract] [Full-text]
42. Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays.
    Br J Cancer, 92(12): 2249-61. [Abstract] [Full-text]
43. Secreted protein acidic and rich in cysteine produced by human melanoma cells modulates polymorphonuclear leukocyte recruitment and antitumor cytotoxic capacity.
    Cancer Res, 65(12): 5123-32. [Abstract] [Full-text]
44. [99mTcOAADT]-(CH2)2-NEt2: a potential small-molecule single-photon emission computed tomography probe for imaging metastatic melanoma.
    Cancer Res, 65(12): 4979-86. [Abstract] [Full-text]
45. Avian adenovirus vector CELO-TK displays anticancer activity in human cancer cells and suppresses established murine melanoma tumors.
    Cancer Gene Ther, 12(7): 617-26. [Abstract] [Full-text]
46. Transcriptional targeting of RGD fiber-mutant adenovirus vectors can improve the safety of suicide gene therapy for murine melanoma.
    Cancer Gene Ther, 12(7): 608-16. [Abstract] [Full-text]
47. The association of Medicare health care delivery systems with stage at diagnosis and survival for patients with melanoma.
    Arch Dermatol, 141(6): 753-7. [Abstract] [Full-text]
48. Early detection of thick melanomas in the United States: beware of the nodular subtype.
    Arch Dermatol, 141(6): 745-50. [Abstract] [Full-text]
49. The role of microsatellites as a prognostic factor in primary malignant melanoma.
    Arch Dermatol, 141(6): 739-42. [Abstract] [Full-text]
50. Impact of thorough block sampling in the histologic evaluation of melanomas.
    Arch Dermatol, 141(6): 734-6. [Abstract] [Full-text]
51. Variation in the diagnosis, treatment, and management of melanoma in situ: a survey of US dermatologists.
    Arch Dermatol, 141(6): 723-9. [Abstract] [Full-text]
52. Correlation between melanoma angiogenesis and the mesenchymal stem cells and endothelial progenitor cells derived from bone marrow.
    Stem Cells Dev, 14(3): 292-8. [Abstract] [Full-text]
53. In vitro response of tumour cells to non-uniform irradiation.
    Phys Med Biol, 50(13): 3041-51. [Abstract] [Full-text]
54. Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines.
    Carcinogenesis, 26(7): 1224-32. [Abstract] [Full-text]
55. Tumour regulation of fibroblast hyaluronan expression: a mechanism to facilitate tumour growth and invasion.
    Carcinogenesis, 26(7): 1215-23. [Abstract] [Full-text]
56. The use of LYVE-1 antibody for detecting lymphatic involvement in patients with malignant melanoma of known sentinel node status.
    J Clin Pathol, 58(7): 715-21. [Abstract] [Full-text]
57. Functionalized pyrrolidines inhibit alpha-mannosidase activity and growth of human glioblastoma and melanoma cells.
    J Med Chem, 48(13): 4237-46. [Abstract] [Full-text]
58. Concurrent loss of chromosome arm 1p and chromosome 3 predicts a decreased disease-free survival in uveal melanoma patients.
    Invest Ophthalmol Vis Sci, 46(7): 2253-7. [Abstract] [Full-text]
59. Predictors of nonsentinel lymph node positivity in patients with a positive sentinel node for melanoma.
    J Am Coll Surg, 201(1): 37-47. [Abstract] [Full-text]
60. Bioluminescent imaging of melanoma in live mice.
    J Invest Dermatol, 125(1): 159-65. [Abstract] [Full-text]
61. Amelanotic malignant melanoma of the esophagus: case report.
    Z Gastroenterol, 43(6): 597-600. [Abstract] [Full-text]
62. Immunological detection of altered signaling molecules involved in melanoma development.
    Cancer Metastasis Rev, 24(2): 357-66. [Abstract] [Full-text]
63. Rb/E2F: a two-edged sword in the melanocytic system.
    Cancer Metastasis Rev, 24(2): 339-56. [Abstract] [Full-text]
64. De-regulation of ubiquitin-dependent proteolysis and the pathogenesis of malignant melanoma.
    Cancer Metastasis Rev, 24(2): 329-38. [Abstract] [Full-text]
65. Targeting STAT3 affects melanoma on multiple fronts.
    Cancer Metastasis Rev, 24(2): 315-27. [Abstract] [Full-text]
66. Role of nuclear factor-kappa B in melanoma.
    Cancer Metastasis Rev, 24(2): 301-13. [Abstract] [Full-text]
67. Protein kinase C in melanoma.
    Cancer Metastasis Rev, 24(2): 287-300. [Abstract] [Full-text]
68. Functional and therapeutic significance of Akt deregulation in malignant melanoma.
    Cancer Metastasis Rev, 24(2): 273-85. [Abstract] [Full-text]
69. SKI pathways inducing progression of human melanoma.
    Cancer Metastasis Rev, 24(2): 265-72. [Abstract] [Full-text]
70. Bone morphogenetic proteins in melanoma: angel or devil?
    Cancer Metastasis Rev, 24(2): 251-63. [Abstract] [Full-text]
71. A Wnt-er wonderland--the complexity of Wnt signaling in melanoma.
    Cancer Metastasis Rev, 24(2): 237-50. [Abstract] [Full-text]
72. Activated leukocyte cell adhesion molecule (ALCAM/CD166): signaling at the divide of melanoma cell clustering and cell migration?
    Cancer Metastasis Rev, 24(2): 223-36. [Abstract] [Full-text]
73. Integrin signaling in malignant melanoma.
    Cancer Metastasis Rev, 24(2): 195-222. [Abstract] [Full-text]
74. A mutation hotspot at the p14ARF splice site.
    Oncogene, 24(28): 4604-8. [Abstract] [Full-text]
75. Perineural extension of facial melanoma.
    Neuroradiology, 47(5): 372-4. [Abstract] [Full-text]

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